Effect of eight weeks of aerobic-resistance training on stromal cell-derived factor-1 and platelet-derived growth factor level in patients with coronary artery bypass grafting: A clinical trial study

Autor: Seyed Hadi Seyedi, Rambod Khajei, Amir Rashidlamir, Mohammad Reza Ramezanpour, Jamshid Mehrzad
Jazyk: perština
Rok vydání: 2021
Předmět:
Zdroj: مجله دانشگاه علوم پزشکی گرگان, Vol 23, Iss 2, Pp 16-23 (2021)
Druh dokumentu: article
ISSN: 1562-4765
2008-4080
96390115
Popis: Background and Objective: Exercise in cardiac patients after coronary artery bypass grafting (CABG) improves cardiovascular function by increasing the capillary density of the myocardium. Platelet-derived growth factor and stromal cell-derived factor-1 play an important role in angiogenesis and cell proliferation and differentiation. This study was performed to determine the effect of eight weeks of combined training on plasma levels of Platelet-derived growth factor (PDGF) and stromal cell-derived factor-1 (SDF1) in CABG patients. Methods: In this clinical trial study, 24 patients who underwent coronary artery bypass grafting operation were selected using convenience and purposeful sampling method and randomly divided into two combined training and control groups. Subjects in combined training group were received aerobic and resistance training protocols for eight weeks, three sessions per week. Before and after training program, body composition assessments and blood sampling were performed to measure Platelet-derived growth factor (PDGF) and stromal cell-derived factor-1 (SDF1). ELISA method was used to measure PDGF and SDF1. Results: The level of PDGF was significantly increased in intervention group in compared to control group (P
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