Maternal chitosan oligosaccharide supplementation during late gestation and lactation optimizes placental function in sows and intestinal function in 21-day-old IUGR suckling piglets

Autor: Xintao Wang, Tingting Fang, Daiwen Chen, Junning Pu, Gang Tian, Jun He, Ping Zheng, Xiangbing Mao, Aimin Wu, Bing Yu
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Frontiers in Veterinary Science, Vol 11 (2024)
Druh dokumentu: article
ISSN: 2297-1769
DOI: 10.3389/fvets.2024.1463707
Popis: Maternal dietary supplementation with chitosan oligosaccharide (COS) has been considered as a potential intervention to mitigate the occurrence of intrauterine growth restriction (IUGR) and improve postnatal growth. The present study investigated the effect of COS as a dietary supplement for sows during late gestation and lactation on their productivity, placental function, and the intestinal health of IUGR piglets. From day (d) 85 of late gestation to d 21 of lactation, 30 sows were randomly divided into either a control group (basal diet) or a COS group (basal diet + 100 mg kg−1 COS). At d 21 of lactation, eight normal and eight IUGR littermates from eight litters belong to control sows, as well as eight IUGR littermates from COS sows, were selected for further analysis. The results showed a significant reduction in the number of stillbirths and mummies in COS groups (p
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