Immune thrombocytopenic purpura in ulcerative colitis: a case report and systematic review

Autor:	Subhash Chandra, Sarah Finn, Eugene Obah
Jazyk:	angličtina
Rok vydání:	2014
Předmět:	immune thrombocytopenic purpura ulcerative colitis anti-tumor necrosis factor antibodies intravenous immunoglobulins extraintestinal manifestation Internal medicine RC31-1245
Zdroj:	Journal of Community Hospital Internal Medicine Perspectives, Vol 4, Iss 0, Pp 1-5 (2014)
Druh dokumentu:	article
ISSN:	2000-9666
DOI:	10.3402/jchimp.v4.23386
Popis:	Over 100 extraintestinal manifestations are reported in ulcerative colitis (UC). A commonly reported hematological manifestation is autoimmune hemolytic anemia. On rare occasions, immune thrombocytopenic purpura (ITP) has been reported with UC. The presence of thrombocytopenia can complicate the clinical scenario as the number of bloody bowel movements is an important indicator of disease activity in UC. A proposed theory for this association is antigenic mimicry between a platelet surface antigen and bacterial glycoprotein. We are reporting a case of UC and associated ITP managed successfully with anti-TNF therapy. We also performed a systemic review of case reports and a case series reporting this association.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/1a5d85cb2ab244768662e83b71060803 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF Plný text ve formátu HTML
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