Autor: |
Mohamed A.M. Alsafy, Islam A. Abdellatif, Samir A. A. El-Gendy, Mohamed M.A. Abumandour, Ahmed Noreldin, Naglaa F. Bassuoni |
Jazyk: |
angličtina |
Rok vydání: |
2024 |
Předmět: |
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Zdroj: |
BMC Veterinary Research, Vol 20, Iss 1, Pp 1-13 (2024) |
Druh dokumentu: |
article |
ISSN: |
1746-6148 |
DOI: |
10.1186/s12917-024-04253-y |
Popis: |
Abstract Background Sodium butyrate is a potential antibiotic growth promoter and has had advantageous effects on the poultry industry. Methods Evaluating the effect of sodium butyrate on the intestinal villi and the humoral part of innate immunity of the male Cobb 500 broiler using scanning electron microscopy and quantitative real-time PCR analysis, the control group and treated group of Cobb 500 with SB supplemented received water containing 0.98 mg sodium butyrate. Results The administration of sodium butyrate changed the villi characters, as the shape changed from tongue to long tongue. They were mainly parallel to each other and long finger-like at the duodenum. The tips of the villi in the control group appeared thin-slight curved with a prominent center in the duodenum, thin rectangular in the jejunum, and ileum in the control group. In contrast, in the treatment group, they changed to thick rectangular in the duodenum and ileum zigzag shape in the jejunum. The epithelium lining of the duodenal villi showed a dome shape, the jejunal villi showed a polygonal shape, and the ileal villi appeared scales-like. The epithelium lining showed irregular microfolds and many different-sized pores, and the treatment group showed islands of long microvilli in the duodenum and solitary long microvilli in the ileum. Real-time PCR of AvBD 1, 2, 10, and 12 significantly (P |
Databáze: |
Directory of Open Access Journals |
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