Altered Ca2+-Homeostasis of Cisplatin-Treated and Low Level Resistant Non-Small-Cell and Small-Cell Lung Cancer Cells

Autor: Kathrin Schrödl, Hamza Oelmez, Martin Edelmann, Rudolf Maria Huber, Albrecht Bergner
Jazyk: angličtina
Rok vydání: 2009
Předmět:
Zdroj: Cellular Oncology, Vol 31, Iss 4, Pp 301-315 (2009)
Druh dokumentu: article
ISSN: 1570-5870
1875-8606
DOI: 10.3233/CLO-2009-0472
Popis: Background: Chemotherapy often leads to encouraging responses in lung cancer. But, in the course of the treatment, resistance to chemotherapy ultimately limits the life expectancy of the patient. We aimed at investigating if treatment with cisplatin alters the intracellular Ca2+-homeostasis of lung cancer cells and how this may be related to cisplatin resistance.
Databáze: Directory of Open Access Journals