A case of naturally occurring anti-Dia antibody in a young man

Autor: Salfarina Iberahim, Noor Haslina Mohd Noor, Mohd Nazri Hassan, Rosnah Bahar, Shafini Mohdmed Yusoff, Marini Ramli, Wan Suriana Wan Abdul Rahman, Zefarina Zulkafli, Marne Abdullah, Ho Sook Fong, Tengku Muzaffar Tengku Mohamed Shihabudin, Hisham Atan Edinur, Norul Hajar Che Ghazali
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Asian Journal of Transfusion Science, Vol 16, Iss 2, Pp 276-279 (2022)
Druh dokumentu: article
ISSN: 0973-6247
1998-3565
DOI: 10.4103/ajts.ajts_136_21
Popis: The Diego (Di) blood group system comprises 22 antigens located on the band 3 protein, most of which are low-prevalence antigens. The majority of antibodies to Diego system antigens were of clinically insignificant; however anti-Dia, -Dib, -Wra, -ELO and-DISK may cause hemolytic disease of the fetus and newborn (HDFN) and transfusion reaction. We reported a case of naturally occurring of anti-Dia in a young man who presented to our hospital for wound debridement of fingers injury. His serological results were suggestive of anti-Dia antibody, and his molecular blood group showed he has Di (a-b+) antigen. Anti-Dia may be clinically significant. It can cause mild-to-severe HDFN, but there are only infrequent reports of it being clearly implicated in a hemolytic transfusion reaction. We suggest the need for reagent red blood cell panels to include Dia antigen-positive cells in antibody identification tests for our populations.
Databáze: Directory of Open Access Journals
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