| Autor: |
Yuki Iida, Kuniyasu Kamiya, Takuji Adachi, Kotaro Iwatsu, Kenta Kamisaka, Naoki Iritani, Shota Imoto, Sumio Yamada, the FLAGSHIP collaborators |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
ESC Heart Failure, Vol 10, Iss 6, Pp 3364-3372 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2055-5822 |
| DOI: |
10.1002/ehf2.14519 |
| Popis: |
Abstract Aims Malnutrition is prevalent among patients with heart failure (HF); however, the effects of coexisting malnutrition and frailty on prognosis are unknown. This study examines the impact of malnutrition and frailty on the prognosis of patients with HF. Methods and results We examined 1617 patients with HF aged 65 years or older (age: 78.6 ± 7.4; 44% female) from a Japanese multicentre prospective cohort study. The nutritional status was evaluated using the Geriatric Nutritional Risk Index (GNRI), Controlling Nutritional Status (CONUT), and Mini Nutritional Assessment Short Form on discharge. Frailty was assessed using the criteria determined in a previous study on patients with HF. The prognostic impact of each nutrition measure on the risk of composite all‐cause mortality and cardiac readmissions within 2 years of hospital discharge was assessed using Kaplan–Meier survival curves and Cox proportional hazards model analysis for non‐frail and frail groups. Over 2324.2 person‐years of follow‐up, 88 patients died and 448 patients experienced readmission due to HF. In the non‐frail group, poor nutritional status assessed using the GNRI and CONUT was associated with an increased hazard ratio (HR) of composite outcomes in the crude model; however, adjustment for potential confounders diminished the association. In the frail group, all three nutritional indicators were associated with the cumulative incidence of the study outcome (log‐rank test, P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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