Interrelationship between serum and sputum inflammatory mediators in chronic obstructive pulmonary disease
| Autor: | L. Bizeto, A.B. Mazzolini, M. Ribeiro, R. Stelmach, A. Cukier, M.P.T. Nunes |
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| Jazyk: | angličtina |
| Rok vydání: | 2008 |
| Předmět: | |
| Zdroj: | Brazilian Journal of Medical and Biological Research, Vol 41, Iss 3, Pp 193-198 (2008) |
| Druh dokumentu: | article |
| ISSN: | 0100-879X 1414-431X |
| Popis: | Little is known about airway inflammatory markers in chronic obstructive pulmonary disease (COPD). The objective of the present study was to identify and try to correlate pulmonary and peripheral blood inflammatory markers in COPD. In a cross-sectional study on patients with stable COPD, induced sputum and blood samples were collected for the determination of C-reactive protein, eosinophilic cationic protein, serum amyloid A protein, a-1 antitrypsin (a-1AT), and neutrophil elastase. Twenty-two patients were divided into two groups according to post-bronchodilator forced expiratory volume in the first second (%FEV1): group 1 (N = 12, FEV1 |
| Databáze: | Directory of Open Access Journals |
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