Human adenovirus among hospitalized children with respiratory tract infections in Beijing, China, 2017–2018

Autor: Li-hong Yao, Chao Wang, Tian-li Wei, Hao Wang, Fen-lian Ma, Li-shu Zheng
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Virology Journal, Vol 16, Iss 1, Pp 1-8 (2019)
Druh dokumentu: article
ISSN: 1743-422X
DOI: 10.1186/s12985-019-1185-x
Popis: Abstract Background Human adenoviruses (HAdVs) cause a wide range of diseases. However, the genotype diversity and epidemiological information relating to HAdVs among hospitalized children with respiratory tract infections (RTIs) is limited. Here, we describe the epidemiology and genotype distribution of HAdVs associated with RTIs in Beijing, China. Methods Nasopharyngeal aspirates (NPA) were collected from hospitalized children with RTIs from April 2017 to March 2018. HAdVs were detected by a TaqMan-based quantitative real-time polymerase chain reaction (qPCR) assay, and the hexon gene was used for phylogenetic analysis. Epidemiological data were analyzed using statistical product and service solutions (SPSS) 21.0 software. Results HAdV was detected in 72 (5.64%) of the 1276 NPA specimens, with most (86.11%, 62/72) HAdV-positives cases detected among children
Databáze: Directory of Open Access Journals
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