Molecular correlates of muscle spindle and Golgi tendon organ afferents

Autor: Katherine M. Oliver, Danny M. Florez-Paz, Tudor Constantin Badea, George Z. Mentis, Vilas Menon, Joriene C. de Nooij
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-021-21880-3
Popis: Coordinated movement critically depends on sensory feedback from muscle spindles (MSs) and Golgi tendon organs (GTOs) but the afferents supplying this proprioceptive feedback have remained genetically inseparable. Here the authors use single cell transcriptome analysis to reveal the molecular basis of MS (groups Ia and II) and GTO (group Ib) afferent identities in the mouse.
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