Co-downregulation of GRP78 and GRP94 induces apoptosis and inhibits migration in prostate cancer cells

Autor: Lu Tong, Wang Yue, Xu Kang, Zhou Zhijun, Gong Juan, Zhang Yingang, Gong Hua, Dai Qiang, Yang Jun, Xiong Biao, Song Ze, Yang Gang
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Open Life Sciences, Vol 14, Iss 1, Pp 384-391 (2019)
Druh dokumentu: article
ISSN: 2391-5412
DOI: 10.1515/biol-2019-0043
Popis: Both glucose-regulated protein 78 kDa (GRP78) and glucose-regulated protein 94 kDa (GRP94) are important molecular chaperones that play critical roles in maintaining tumor survival and progression. This study investigated the effects in prostate cancer cells following the downregulation of GRP78 and GRP94.
Databáze: Directory of Open Access Journals