Evaluation of drug information resources for drug-ethanol and drug-tobacco interactions

Autor: Robert D. Beckett, Curtis D. Stump, Megan A. Dyer
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Journal of the Medical Library Association, Vol 107, Iss 1 (2019)
Druh dokumentu: article
ISSN: 1536-5050
1558-9439
DOI: 10.5195/jmla.2019.549
Popis: Objective: The research evaluated point-of-care drug interaction resources for scope, completeness, and consistency in drug-ethanol and drug-tobacco content. Methods: In a cross-sectional analysis, 2 independent reviewers extracted data for 108 clinically relevant interactions using 7 drug information resources (Clinical Pharmacology Drug Interaction Report, Facts & Comparisons eAnswers, Lexicomp Interactions, Micromedex Drug Interactions, Drug Interactions Analysis and Management, Drug Interaction Facts, and Stockley’s Drug Interactions). Scope (presence of an entry), completeness (content describing mechanism, clinical effects, severity, level of certainty, and course of action for each present interaction; up to 1 point per assessed item for a total possible score of 5 points), and consistency (similarity among resources) were evaluated. Results: Fifty-three drug-ethanol and 55 drug-tobacco interactions were analyzed. Drug-ethanol interaction entries were most commonly present in Lexicomp (84.9%), Clinical Pharmacology (83.0%), and Stockley’s Drug Interactions (73.6%), compared to other resources (p
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