A childhood acute lymphoblastic leukemia (ALL) case with t(3;17)(q23;p13),t(5;12)(q31;p13),inv(11)(p15q12)

Autor: Ayse Cirakoglu, Ayhan Deviren, Yelda Tarkan-Arguden, Seniha Hacihanefioglu, Cengiz Canpolat, Su Gulsun Berrak, Sukriye Yilmaz, Dilhan Kuru
Jazyk: angličtina
Rok vydání: 2008
Předmět:
Zdroj: Turkish Journal of Hematology, Vol 25, Iss 03, Pp 152-154 (2008)
Druh dokumentu: article
ISSN: 1300-7777
1308-5263
Popis: It is known that clonal chromosomal changes in childhood ALL are nonrandom and important markers for diagnosis, prognosis and relaps. In this report we present 4 year-old boy with ALL-L1 who has complex chromosomal rearrangements. Chromosome analysis was performed on bone marrow aspiration sample in relaps after one year from diagnosis and induction chemotherapy. The karyotype was; 46,XY,t(3;17)(q23;p13),t(5;12)(q31;p13),inv(11)(p15q12) [11]/46,XY[8]
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