Cell-based therapy in the management of Class III Miller's recession – A case report with 45-month follow-up

Autor: R P Meenakshi, R Kiruba, K V Arun, G Sivaram, Deepavalli Arumuganainar, K Kaveri
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of Indian Society of Periodontology, Vol 27, Iss 4, Pp 437-442 (2023)
Druh dokumentu: article
ISSN: 0972-124X
DOI: 10.4103/jisp.jisp_436_22
Popis: Miller's Class III gingival recessions (GRs) have always posed a challenge to the clinicians in terms of achieving complete root coverage (CRC). In the present case, a cell-based therapy with autologous fibroblasts seeded onto a Type 1 collagen membrane, through an in-vitro culturing method was utilized. The fibroblasts-seeded membrane was surgically placed under a laterally repositioned flap. The patient presented with a CRC, which was stable even at the postoperative period of 45 months. In addition, a 3-mm substantial gain in the width of keratinized tissue was achieved and maintained throughout the postoperative period. Hence, the results of the cell-seeded therapy emphasize that it can serve as an effective alternative method for the management of Miller's Class III GRs.
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