Supplementation with Ziziphus Jujuba Suppresses Apoptosis Signals in Neutrophils after Acute Exercise
| Autor: | Seyed Morteza Tayebi, Karsten Krüger, Farahnaz Ebrahimi, Abbas Izadi, Maryam Roushan, Anna V. Nenasheva |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | Montenegrin Journal of Sports Science and Medicine, Vol 10, Iss 2, Pp 31-39 (2021) |
| Druh dokumentu: | article |
| ISSN: | 1800-8755 1800-8763 |
| DOI: | 10.26773/mjssm.210905 |
| Popis: | It is suggested that jujube might benefit exercise-induced immune fluctuations, specifically on neutrophils’ apoptosis regulation, but its cellular mechanism is unclear. This study aimed to investigate the effect of one-week supplemen- tation with Ziziphus jujuba on pro- and anti-apoptotic protein levels of neutrophils in response to a session of circuit resistance exercise. Fourteen young, healthy male students completed a session of circuit resistance exercise (75% 1RM, nine exercises, three sets) in two groups (n=7). While one group received a placebo, the other group was supplemented with jujube (0.5 g/kg body weight suspended in 2.5 cc distilled water) started a weekday before the exercise session. Blood samples were collected 30 minutes before, immediately, and two hours after the exercise. Neutrophils were col- lected and pro- (Calpain-1, Bax, Caspase-3) and anti-apoptotic (Calpastatin, XIAP) proteins measured with ELISA. In- tracellular calcium ([Ca 2+ ]i) was assessed using the Atomic Absorption/ Flame Emission method. Repeated-Measures ANOVA was used for the interaction effects of TIME×GROUP (3×2) at the significance level (p) of 0.05. The SPSS software was used for analyses. Levels of ([Ca 2+ ]i), expression of calpain-, and caspase-3 were increased in response to circuit resistance exercise (p |
| Databáze: | Directory of Open Access Journals |
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