Nomogram to predict severe retinopathy of prematurity in Southeast China

Autor: Dan Liu, Xing-Yong Li, Hong-Wu He, Ka-Lu Jin, Ling-Xia Zhang, Yang Zhou, Zhi-Min Zhu, Chen-Chen Jiang, Hai-Jian Wu, Sui-Lian Zheng
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: International Journal of Ophthalmology, Vol 17, Iss 2, Pp 282-288 (2024)
Druh dokumentu: article
ISSN: 2222-3959
2227-4898
DOI: 10.18240/ijo.2024.02.09
Popis: AIM: To define the predictive factors of severe retinopathy of prematurity (ROP) and develop a nomogram for predicting severe ROP in southeast China. METHODS: Totally 554 infants diagnosed with ROP hospitalized in the Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University and hospitalized in Taizhou Women and Children's Hospital were included. Clinical data and 43 candidate predictive factors of ROP infants were collected retrospectively. Logistic regression model was used to identify predictive factors of severe ROP and to propose a nomogram for individual risk prediction, which was compared with WINROP model and Digirop-Birth model. RESULTS: Infants from the Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University (n=478) were randomly allocated into training (n=402) and internal validation group (n=76). Infants from Taizhou Women and Children's Hospital were set as external validation group (n=76). Severe ROP were found in 52 of 402 infants, 12 of 76 infants, and 7 of 76 infants in training group, internal validation group, and external validation group, respectively. Birth weight [odds ratio (OR), 0.997; 95% confidence interval (CI), 0.996-0.999; P
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