Intracerebral Hemorrhage: Blood Components and Neurotoxicity

Autor: Neha Madangarli, Frederick Bonsack, Rajaneekar Dasari, Sangeetha Sukumari–Ramesh
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Brain Sciences, Vol 9, Iss 11, p 316 (2019)
Druh dokumentu: article
ISSN: 2076-3425
DOI: 10.3390/brainsci9110316
Popis: Intracerebral hemorrhage (ICH) is a subtype of stroke which is associated with the highest mortality and morbidity rates of all strokes. Although it is a major public health problem, there is no effective treatment for ICH. As a consequence of ICH, various blood components accumulate in the brain parenchyma and are responsible for much of the secondary brain damage and ICH-induced neurological deficits. Therefore, the strategies that could attenuate the blood component-induced neurotoxicity and improve hematoma resolution are highly needed. The present article provides an overview of blood-induced brain injury after ICH and emphasizes the need to conduct further studies elucidating the mechanisms of hematoma resolution after ICH.
Databáze: Directory of Open Access Journals
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