High-frequency oscillatory ventilation in children: a 10-year experience

Autor: Marta Moniz, Catarina Silvestre, Pedro Nunes, Clara Abadesso, Ester Matias, Helena Loureiro, Helena Almeida
Jazyk: portugalština
Rok vydání: 2013
Předmět:
Zdroj: Jornal de Pediatria (Versão em Português), Vol 89, Iss 1, Pp 48-55 (2013)
Druh dokumentu: article
ISSN: 2255-5536
DOI: 10.1016/j.jpedp.2012.08.005
Popis: Objectives: The aim of the study was to describe the experience with high-frequency oscillatory ventilation (HFOV) in a Portuguese Pediatric Critical Care Unit, and to evaluate whether HFOV allowed improvement in oxygenation and ventilation. Methods: This was a retrospective observational cohort study of children ventilated by HFOV between January, 2002 and December, 2011. The following parameters were recorded: demographic and clinical data, and blood gases and ventilatory parameters during the first 48 hours of HFOV. Results: 80 children were included, with a median age of 1.5 months (min: one week; max: 36 months). Pneumonia (n = 50; 62.5%) and bronchiolitis (n = 18; 22.5%) were the main diagnoses. Approximately 40% (n = 32) of the patients developed acute respiratory distress syndrome (ARDS). Conventional mechanical ventilation was used in 68 (85%) of patients prior to HFOV. All patients who started HFOV had hypoxemia, and 56 (70%) also presented persistent hypercapnia. Two hours after starting HFOV, a significant improvement in SatO2/FiO2 ratio (128 ± 0.63 vs. 163 ± 0.72; p
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