Evaluation of the Effect of Benzydamine Hydrochloride on the Intensity of Gag Reflex: A Randomized Single-Blind Clinical Trial

Autor: Mohammad Mehdi Torabi, Reyhaneh Shoorgashti, Farnaz Haji Fattahi, Simin Lesan
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Journal of Dentistry, Vol 25, Iss 2, Pp 162-168 (2024)
Druh dokumentu: article
ISSN: 2345-6485
2345-6418
DOI: 10.30476/dentjods.2023.97675.2032
Popis: Statement of the Problem: Gag reflex is among the most common problems during dental and endoscopic procedures. Benzydamine hydrochloride is a non-steroidal anti-inflammatory medica-tion and a local anesthetic that might be useful in reducing the gag reflex. Purpose: This study aimed to evaluate the effects of benzydamine hydrochloride mouthwash on the intensity of the gag reflex.Materials and Method: In this randomized clinical trial study, 30 participants aged 21-26 with a gag trigger point index (GTPI) higher than 2 were divided into 2 groups. In the case group, 15 ml of 0.15% benzydamine hydrochloride mouthwash was gargled for 1 minute, and after 10 minutes GTPI test was conducted. In the control group, 4 puffs of 10% lidocaine spray were applied to the mucosa of the targeted area, and after 5 minutes, GTPI was measured. Participants were asked about the taste and smell of the medications. Results: GTPI was significantly reduced in both groups. In the lidocaine group, the GTPI score changed from 4.47 to 2.00 (P
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