Additional diagnostic immunocytochemical criteria for T/NK-cell lymphomas

Autor:	I. B. Kovynev, T. I. Pospelova, E. N. Voropaeva, N. J. Djachkova, N. V. Skvortsova, A. S. Ljamkina, I. N. Nechunaeva
Jazyk:	ruština
Rok vydání:	2022
Předmět:	non-hodgkin's t-cell lymphomas classification of t-cell neoplasms additional quantitative immunocytochemical criteria Diseases of the blood and blood-forming organs RC633-647.5
Zdroj:	Онкогематология, Vol 0, Iss 3, Pp 9-14 (2022)
Druh dokumentu:	article
ISSN:	1818-8346 2413-4023
DOI:	10.17650/1818-8346-2007-0-3-9-14
Popis:	896 patients (pts) with malignant non-Hodgkin's lymphomas were examined in this study. Т-cell immunophenotype has been established in 208 cases. Diagnosis was established according to the WHO criteria. We used the panel from 15 monoclonal antibodies for the detailed characteristic of Т-cell immunophenotype of non-Hodgkin's lymphomas. Lymphoblastic lymphomas was revealed in 115 pts and peripheral T-lymphomas in 93 pts. It was shown, that immunocytochemical research with quantitative calculation of antigen-positive cells has the certain value for differential diagnostics of peripheral Tcell lymphomas. We determined some quantitative diagnostics criteria in addition to WHO classification and proved their evidence in malignancy heterogeneity typical for T-cell lymphomas.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/a19b2a17ec6a49d4a8354699c5768942 Zobrazit plný text záznamu View record in DOAJ