Investigating the Electric Field Lysis of Exosomes Immobilized on the Screen-Printed Electrode and Electrochemical Sensing of the Lysed-Exosome-Derived Protein

Autor: Krishna Thej Pammi Guru, Nusrat Praween, Palash Kumar Basu
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Biosensors, Vol 13, Iss 3, p 323 (2023)
Druh dokumentu: article
ISSN: 2079-6374
DOI: 10.3390/bios13030323
Popis: It is important to isolate exosomes (8 exosomes/mL were isolated from serum. With the limit of detection of 10 pg, the designed cell showed a linear detection of HER2 from 0.1 ng to 1 µg. It was observed from the results that the electric field lysis of exosomes not only plays a significant role in releasing the cargo protein but also improves the sensing of surface proteins associated with exosomes.
Databáze: Directory of Open Access Journals