Case Report: CBD Cigarettes for Harm Reduction and Adjunctive Therapy in a Patient With Schizophrenia and Substance Use Disorder

Autor: Maximilian Meyer, Marc Walter, Stefan Borgwardt, Alexandra Scheidegger, Elisabeth Lang, Patrick Köck
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Frontiers in Psychiatry, Vol 12 (2021)
Druh dokumentu: article
ISSN: 1664-0640
DOI: 10.3389/fpsyt.2021.712110
Popis: The treatment of patients with schizophrenia and substance use disorder poses a challenge for clinicians. Continued use of cannabis and cocaine can exacerbate psychotic symptoms and worsen the course of disease. To date, no pharmacotherapy is available for patients with cannabis use disorder (CUD). Cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC) are the main active constituents in Cannabis sativa, with the latter being linked to an increased risk of psychosis. We describe a clinical case of a male patient diagnosed with schizophrenia, combined personality disorder, CUD and cocaine use disorder. Over the course of 8 years, he was hospitalized 30 times due to psychotic relapses and continued substance use. Consequently, CBD cigarettes with a low THC content (
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