Implantable loop recorder in Brugada syndrome: Insights from a single-center experience

Autor: Gianmarco Arabia, Manuel Cerini, Angelica Cersosimo, Paolo Vinciguerra, Emiliano Calvi, Gianfranco Mitacchione, Mohamed Aboelhassan, Daniele Giacopelli, Antonio Curnis
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: International Journal of Cardiology: Heart & Vasculature, Vol 51, Iss , Pp 101371- (2024)
Druh dokumentu: article
ISSN: 2352-9067
DOI: 10.1016/j.ijcha.2024.101371
Popis: Background: This study aimed to investigate the characteristics and outcomes of patients diagnosed with Brugada syndrome (BrS) who underwent implantable loop recorder (ILR) insertion during routine clinical activity. Methods: We conducted a comprehensive screening of all consecutive patients diagnosed with BrS at our institution. We analyzed baseline clinical characteristics, arrhythmic findings, and outcomes. Results: Out of 147 BrS patients, 42 (29 %) received an ILR, 13 (9 %) underwent implantable cardioverter-defibrillator (ICD) placement, and 92 patients (63 %) continued regular cardiological follow-up. Patients who received an ILR had a higher prevalence of suspected arrhythmic syncope (43 % vs. 22 %, p = 0.012) and tended to be younger (median age 38 years, interquartile range 30–52, vs. 43 years, 35–55, p = 0.044) with a higher presence of SCN5A gene mutations (17 % vs. 6 %, p = 0.066) compared to those who continued regular follow-up. Additionally, compared to patients with an ICD, those with an ILR had a significantly lower frequency of positive programmed ventricular stimulation (0 % vs. 91 %, p
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