Discovery of 'Molecular Switches' within a Series of mGlu5 Allosteric Ligands Driven by a 'Magic Methyl' Effect Affording Both PAMs and NAMs with In Vivo Activity, Derived from an M1 PAM Chemotype
Autor: | Lisa Barbaro, Alice L. Rodriguez, Ashlyn N. Blevins, Jonathan W. Dickerson, Natasha Billard, Olivier Boutaud, Jerri L. Rook, Colleen M. Niswender, P.Jeffrey Conn, Darren W. Engers, Craig W. Lindsley |
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Jazyk: | angličtina |
Rok vydání: | 2021 |
Předmět: | |
Zdroj: | ACS Bio & Med Chem Au, Vol 1, Iss 1, Pp 21-30 (2021) |
Druh dokumentu: | article |
ISSN: | 2694-2437 |
DOI: | 10.1021/acsbiomedchemau.1c00024 |
Databáze: | Directory of Open Access Journals |
Externí odkaz: |