Clear Cell Myoepithelial Carcinoma Arising from the Hard Palate with Metastasis to the Lungs

Autor: Jiayun Fang, Amanda Kornfield, Alex Clavijo, Shikhar Vyas, Alison Ulbrandt, Carsten Schroeder, J. Kenneth Byrd, Daniel Kleven
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Case Reports in Pathology, Vol 2019 (2019)
Druh dokumentu: article
ISSN: 2090-6781
2090-679X
DOI: 10.1155/2019/3863270
Popis: Myoepithelial carcinoma is an uncommon tumor of the salivary glands, most commonly the parotid gland. Clear cell myoepithelial carcinoma is a rare variant with an aggressive behavior. Here, we describe a case of clear cell myoepithelial carcinoma arising from the hard palate in an elderly male who underwent resection of the tumor and postop radiation. Posttreatment imaging demonstrated bilateral pulmonary nodules and a C2 body lesion concerning for metastasis. Biopsy of the lung lesions revealed a monomorphous population of optically clear cells with hyperchromatic and pleomorphic nuclei which were morphologically similar to the prior resection specimen. There are few reported cases of clear cell myoepithelial carcinoma arising from the hard palate, and there are even fewer reports on metastases to the lungs. Due to the low number of reported cases, prognosis and treatment of this neoplasm is not well defined.
Databáze: Directory of Open Access Journals
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