| Autor: |
Li‐Peng Liu, Ao‐Li Zhang, Min Ruan, Li‐Xian Chang, Fang Liu, Xia Chen, Ben‐Quan Qi, Li Zhang, Yao Zou, Yu‐Mei Chen, Xiao‐Juan Chen, Wen‐Yu Yang, Ye Guo, Xiao‐Fan Zhu |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
Cancer Medicine, Vol 9, Iss 11, Pp 3647-3655 (2020) |
| Druh dokumentu: |
article |
| ISSN: |
2045-7634 |
| DOI: |
10.1002/cam4.3023 |
| Popis: |
Abstract Background The prognosis of children with acute monocytic leukemia (AML‐M5) remains unsatisfactory and the risk profile is still controversial. We aim to investigate the prognostic value of clinical and cytogenetic features and propose a new risk stratification in AML‐M5 children. Methods We included 132 children with AML‐M5. Overall survival (OS) and progression‐free survival (PFS) were documented. Cox regression was performed to evaluate the potential risk factors of prognosis. Results The 5‐year‐OS was 46.0% (95% confidence intervals, 41.6%‐50.4%) in all patients. There was significantly lower OS in the age ≤ 3 years old (P = .009) and hyperleukocytosis (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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