Hematological ratios and indices in canine large B-cell lymphoma
| Autor: | Alessandra Gavazza, Valentina Cremonini, Arianna Miglio, Chiara Starita, Giacomo Rossi, Maria Teresa Antognoni |
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| Jazyk: | angličtina |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Open Veterinary Journal, Vol 14, Iss 4, Pp 980-989 (2024) |
| Druh dokumentu: | article |
| ISSN: | 2226-4485 2218-6050 |
| DOI: | 10.5455/OVJ.2024.v14.i4.5 |
| Popis: | Background: Canine lymphoma is the most common hematopoietic cancer in dogs. Numerous studies have evaluated the prognostic value of hematological abnormalities and ratios in both humans and dogs with lymphoma. Aim: To compare hematological parameters and complete blood count ratios between a population of dogs affected by lymphoma and healthy dogs to identify potential prognostic markers for lymphoma. Methods: This retrospective case-control study compares hematological parameters and complete blood count ratios between a population of 114 dogs affected by Multicentric Large B-Cell Lymphoma (LBCL) and 60 healthy dogs. Results: The study found several statistically significant differences between the hematological indices of LBCL dogs and healthy dogs, but no correlation between these parameters and the survival times of 78 dogs treated with chemotherapy Madison Wisconsin Protocol. Additionally, hematological alterations were evaluated such as anemia, leukocytosis, and thrombocytopenia. Conclusion: Hematological ratios have been suggested as potential prognostic markers for canine LBCL but their real prognostic value remains controversial and requires future investigation. [Open Vet J 2024; 14(4.000): 980-989] |
| Databáze: | Directory of Open Access Journals |
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