The protective effect of rural life on mite sensitization disappears among urban migrants in the South of Vietnam

Autor: Ha Thi Chu, Thanh Ngoc Tran, Virginie Doyen, Olivier Denis, Thi Thu Thuy Tran, Thi Kieu Diem Nguyen, Huu Lan Nguyen, Minh Xuan Ngo, Thi Mong Hiep Tran, Francis Corazza, Catherine Bouland, Jean-Marie Hauglustaine, Isabelle Godin, Olivier Michel
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: World Allergy Organization Journal, Vol 12, Iss 12, Pp - (2019)
Druh dokumentu: article
ISSN: 1939-4551
DOI: 10.1016/j.waojou.2019.100085
Popis: Background: Rapid urbanization combined with rural migration to urban areas in southern Vietnam could be risk factors for allergen sensitization, contributing to chronic respiratory diseases (CRD). We aimed to evaluate the prevalence of mite sensitization and its relation to house dust characteristics among rural and urban native and migrating populations with CRD. Methods: Rural (n = 19) and urban (n = 46) dwellings were defined on the basis of a home typology. Controls were western Belgian houses (n = 14). Besides the house characteristics, both endotoxin and mite allergens were measured in the settled dusts. The sensitization to mite allergens was defined by positive skin prick test (SPT) and concentration of specific IgE (sIgE)≥ 0.7 U/mL. The prevalence of mite sensitization was evaluated among 610 patients with CRD and compared according to both their home types and places of birth and residences. Results: The concentration of endotoxin (but not mite allergen) was higher in rural compared to urban dusts (440 (95%CI: 314–566) versus 170 (95%CI: 115–226) EU/mg; p
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