| Autor: |
Yong Soo Kim, Beom Joon Kim, Bijoy K. Menon, Joonsang Yoo, Jung Hoon Han, Bum Joon Kim, Chi Kyung Kim, Jae Guk Kim, Joon‐Tae Kim, Hyungjong Park, Sung Hyun Baik, Moon‐Ku Han, Jihoon Kang, Jun Yup Kim, Keon‐Joo Lee, Han‐gil Jeong, Jong‐Moo Park, Kyusik Kang, Soo Joo Lee, Jae‐Kwan Cha, Dae‐Hyun Kim, Jin‐Heon Jeong, Tai Hwan Park, Sang‐Soon Park, Kyung Bok Lee, Jun Lee, Keun‐Sik Hong, Yong‐Jin Cho, Hong‐Kyun Park, Byung‐Chul Lee, Kyung‐Ho Yu, Mi‐Sun Oh, Dong‐Eog Kim, Wi‐Sun Ryu, Kang‐Ho Choi, Jay Chol Choi, Joong‐Goo Kim, Jee‐Hyun Kwon, Wook‐Joo Kim, Dong‐Ick Shin, Kyu Sun Yum, Sung‐Il Sohn, Jeong‐Ho Hong, Chulho Kim, Sang‐Hwa Lee, Juneyoung Lee, Hee‐Joon Bae |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Stroke: Vascular and Interventional Neurology, Vol 3, Iss 5 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2694-5746 |
| DOI: |
10.1161/SVIN.122.000819 |
| Popis: |
Background Approximately 10% of patients with acute ischemic stroke with large‐vessel occlusion (LVO) have mild neurological deficits. Although leptomeningeal collaterals (LMCs) are the major determinant of clinical outcomes for patients with acute ischemic stroke with LVO, the contribution of baseline LMC status to subsequent infarct progression in patients with mild stroke with LVO is poorly defined. Methods This observational study included patients with acute anterior circulation LVO and mild stroke symptoms (National Institutes of Health Stroke Scale < 6) from a prospectively collected, multicenter, national stroke registry. The Alberta Stroke Program Early Computed Tomography Score was quantified on the initial and follow‐up images. An infarct progression, defined as any Alberta Stroke Program Early Computed Tomography Score decrease between the initial versus follow‐up scans, was categorized as either 0/1/2+. The LMCs on the baseline images were graded as good, fair, or poor. Results Of the 623 included patients (mean age, 67.6±13.4 years; 380 [61.0%] men; 186 [29.9%] with reperfusion treatment), the baseline LMC was graded as good in 331 (53.1%), fair in 219 (35.2%), and poor in 73 (11.7%). The Alberta Stroke Program Early Computed Tomography Score decrement was noted as 0 in 288 (46%) patients, 1 in 154 (24%), and 2+ in 181 (29%). A poor LMC was associated with an infarct progression (adjusted odds ratio, 2.05 [95% CI, 1.22–3.47]). Conclusions Poor collateral blood flow was associated with infarct progression in patients with acute ischemic stroke with LVO and mild symptoms. In this selective population, early assessment of collateral blood flow status can help in early detection of patients susceptible to infarct progression. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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