| Autor: |
Manato Kanesaka, Shinichi Sakamoto, Yasutaka Yamada, Junryo Rii, Maihulan Maimaiti, Tomokazu Sazuka, Yusuke Imamura, Akira Komiya, Koichiro Akakura, Yuzuru Ikehara, Hiroomi Nakatsu, Tomohiko Ichikawa |
| Jazyk: |
angličtina |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Prostate International, Vol 9, Iss 4, Pp 208-214 (2021) |
| Druh dokumentu: |
article |
| ISSN: |
2287-8882 |
| DOI: |
10.1016/j.prnil.2021.06.001 |
| Popis: |
Background: To identify the real high-risk group among Japanese de novo metastatic prostate cancer patients who fit CHAARTED or LATITUDE criteria. Methods: We retrospectively studied patients who fitted CHAARTED (292 patients) and LATITUDE (294 patients) criteria from Japanese multi-institutions. All patients received androgen deprivation therapy with bicalutamide as an initial treatment. Factors related to overall survival (OS) and progression-free survival were statistically analyzed. Results: The median OS was 55.5 months and 60.0 months in patients who met the CHAARTED and the LATITUDE criteria, respectively. In patients who met CHAARTED criteria, lactate dehydrogenase (LDH) (hazard ratio (HR) 2.63, P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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