Oromandibular Dyskinesia as the Initial Manifestation of Late-Onset Huntington Disease
| Autor: | Dong-Seok Oh, Eun-Seon Park, Seong-Min Choi, Byeong-Chae Kim, Myeong-Kyu Kim, Ki-Hyun Cho |
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| Jazyk: | angličtina |
| Rok vydání: | 2011 |
| Předmět: | |
| Zdroj: | Journal of Movement Disorders, Vol 4, Iss 2, Pp 75-77 (2011) |
| Druh dokumentu: | article |
| ISSN: | 2005-940X 2093-4939 |
| DOI: | 10.14802/jmd.11016 |
| Popis: | Huntington’s disease (HD) is a neurodegenerative disorder characterized by a triad of choreoathetosis, dementia and dominant inheritance. The cause of HD is an expansion of CAG trinucleotide repeats in the HD gene. Typical age at onset of symptoms is in the 40s, but the disorder can manifest at any time. Late-onset (≥ 60 years) HD is clinically different from other adult or juvenile onset HD and characterized by mild motor problem as the initial symptoms, shorter disease duration, frequent lack of family history, and relatively low CAG repeats expansion. We report a case of an 80-year-old female with oromandibular dyskinesia as an initial manifestation of HD and 40 CAG repeats. |
| Databáze: | Directory of Open Access Journals |
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