A Review of Cinnamic Acid’s Skeleton Modification: Features for Antibacterial-Agent-Guided Derivatives

Autor: Rose Malina Annuur, Desita Triana, Teni Ernawati, Yuta Murai, Muhammad Aswad, Makoto Hashimoto, Zetryana Puteri Tachrim
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Molecules, Vol 29, Iss 16, p 3929 (2024)
Druh dokumentu: article
ISSN: 1420-3049
DOI: 10.3390/molecules29163929
Popis: Antimicrobial resistance has emerged as a significant danger to global health, and the need for more effective antimicrobial resistance (AMR) control has been highlighted. Cinnamic acid is abundant in plant products and is a potential starting material for further modification, focusing on the development of new antimicrobial compounds. In the following review, we describe the classification of critical antibacterial-guided reactions applied to the main skeleton structure of cinnamic acid derivatives over the last decade. Of all of the main parts of cinnamic acids, the phenyl ring and the carboxylic group significantly affect antibacterial activity. The results presented in the following review can provide valuable insights into considerable features in the organic modification of cinnamic acids related to antibacterial medication development and the food industry.
Databáze: Directory of Open Access Journals
Nepřihlášeným uživatelům se plný text nezobrazuje