Autor: |
Suzanne S. Fei, Asia D. Mitchell, Michael B. Heskett, Cathy D. Vocke, Christopher J. Ricketts, Myron Peto, Nicholas J. Wang, Kemal Sönmez, W. Marston Linehan, Paul T. Spellman |
Jazyk: |
angličtina |
Rok vydání: |
2016 |
Předmět: |
|
Zdroj: |
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016) |
Druh dokumentu: |
article |
ISSN: |
2041-1723 |
DOI: |
10.1038/ncomms11588 |
Popis: |
Analysing multiple tumours from the same patient permits the study of the germline contribution to cancer. Here, the authors sequence multiple renal tumours from VHL patients and find that intra-patient tumours are clonally distinct but share some genetic features, suggesting that patient-specific factors influence tumour formation. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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