Antinociceptive Effect of Cinnamon Extract on Formalin Induced Pain in Rat
| Autor: | AR Vahidi Merjardi, MH Dashti-Rahmatabadi, AA Pilavaran, F Farzan |
|---|---|
| Jazyk: | perština |
| Rok vydání: | 2009 |
| Předmět: | |
| Zdroj: | Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, Vol 17, Iss 2, Pp 190-199 (2009) |
| Druh dokumentu: | article |
| ISSN: | 2228-5741 2228-5733 |
| Popis: | Introduction: Since time memorial, herbal medicine has played an important role for relief of various symptoms including pain relief. Many researches have focused on the curative as well as antinociceptive effects of herbal extracts. Cinnamon Zeylanicum has long been prescribed in traditional medicine for the treatment of inflammatory-related diseases such as rheumatisms, bronchitis and muscle pains. However, there is little if any scientific research indicating this effect Methods: This experimental study was carried out in Shaheed Sadoughi Medical School on 25 Wistar Rats (200-300grams) randomly divided into 5 groups. In this study, the analgesic effect of intraperitoneal administration of hydro-alcoholic Cinnamon extract in different doses (50,100,500mg/kg) was assessed by using Formalin Test (for chronic pain) during 1hr. post Formalin injection. Results: Our results indicated that cinnamon extract in high dose (500mg/kg) decreased the chronic pain intensity in the 2nd phase of formalin test. This analgesic effect was significant (P |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|