| Autor: |
Amanda K Steele, Eric J Lee, Brian Vestal, Daniel Hecht, Zachary Dong, Eric Rapaport, John Koeppe, Thomas B Campbell, Cara C Wilson |
| Jazyk: |
angličtina |
| Rok vydání: |
2014 |
| Předmět: |
|
| Zdroj: |
PLoS ONE, Vol 9, Iss 5, p e97171 (2014) |
| Druh dokumentu: |
article |
| ISSN: |
1932-6203 |
| DOI: |
10.1371/journal.pone.0097171 |
| Popis: |
Systemic inflammation is a characteristic of both HIV-1 infection and aging ("inflammaging"). Intestinal epithelial barrier damage (IEBD) and microbial translocation (MT) contribute to HIV-associated inflammation, but their impact on inflammaging remains unclear.Plasma biomarkers for IEBD (iFABP), MT (LPS, sCD14), T-cell activation (sCD27), and inflammation (hsCRP, IL-6) were measured in 88 HIV-1 uninfected (HIV(neg)) and 83 treated, HIV-1-infected (HIV(pos)) adults from 20-100 years old.Age positively correlated with iFABP (r = 0.284, p = 0.008), sCD14 (r = 0.646, p = |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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