Cytomegalovirus infection with lissencephaly

Autor: Joseph Leena, Pushpalatha, Kuruvilla Sarah
Jazyk: angličtina
Rok vydání: 2008
Předmět:
Zdroj: Indian Journal of Pathology and Microbiology, Vol 51, Iss 3, Pp 402-404 (2008)
Druh dokumentu: article
ISSN: 0377-4929
Popis: Lissencephaly is a malformation of the brain in which the brain surface is smooth, rather than convoluted. Among the various causes of lissencephaly, infection by a virus during pregnancy plays an important role. Cytomegalovirus (CMV) is an important pathogen causing this anomaly. We present this case of a young female with 24-week-gestation diagnosed on ultrasound as carrying an anomalous fetus with lissencephalic features. At autopsy, there were multiple intra-nuclear CMV inclusions in the brain and the kidneys. This case is presented for its rarity and for the documentation of the tissue localization of CMV inclusions at autopsy.
Databáze: Directory of Open Access Journals