P-56 EXPERIENCE WITH DEXMEDETOMIDINE IN THE MANAGEMENT OF ALCOHOL WITHDRAWAL SYNDROME FOR PATIENTS WITH CIRRHOSIS

Autor: Liliana Ivonne Gallardo Gonzalez, Jose Luis Perez Hernandez, Maria Fatima Higuera de la Tijera
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Annals of Hepatology, Vol 29, Iss , Pp 101670- (2024)
Druh dokumentu: article
ISSN: 1665-2681
DOI: 10.1016/j.aohep.2024.101670
Popis: Conflict of interest: No Introduction and Objectives: Lorazepam is the first-line treatment in patients with alcohol withdrawal syndrome (AWS). In patients with cirrhosis and AWS, the use of dexmedetomidine (DXM) has been poorly studied. The objective of this study is to report the effect of DXM in patients with cirrhosis and AWS. Patients / Materials and Methods: Observational, retrospective, descriptive and analytical study. Patients with cirrhosis and AWS, treated with lorazepam, DXM, or both, were included. The Clinical Institute Withdrawal Assessment of Alcohol Scale (CIWA-Ar) data was collected before and after treatment; as well as the days of in-hospital stay (IHS). The quantitative variables were summarized using non-parametric descriptive statistics according to the distribution of the variables (average and range); as well as frequencies and percentages in the case of qualitative variables. To compare between three independent groups, the Kruskal-Wallis (KW) and Jonckheere-Terpstra (JT) tests were used. A significant difference was considered one with a value of p
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