| Autor: |
Goda Vaitkevičienė, Rėda Matuzevičienė, Mindaugas Stoškus, Tadas Žvirblis, Lina Ragelienė, Kjeld Schmiegelow |
| Jazyk: |
angličtina |
| Rok vydání: |
2014 |
| Předmět: |
|
| Zdroj: |
Medicina, Vol 50, Iss 1, Pp 28-36 (2014) |
| Druh dokumentu: |
article |
| ISSN: |
1010-660X |
| DOI: |
10.1016/j.medici.2014.05.005 |
| Popis: |
Background: Childhood acute lymphoblastic leukemia (ALL) represents the largest group of pediatric malignancies with long-term survival rates of more than 80% achieved in developed countries. Epidemiological data and survival rates of childhood ALL in Lithuania were lacking. Therefore, the aim of this study was to analyze the population-based long-term treatment results of childhood ALL in Lithuania during 1992–2012. Materials and methods: Data of all 459 children with T-lineage and B-cell precursor ALL treated in Lithuania from 1992 to 2012 were collected and analyzed. Results were compared among four time-periods: 1992–1996 (N = 132), 1997–2002 (N = 136), 2003–2008 (N = 109) and 2009–2012 (N = 82). Results: The incidence of childhood ALL in Lithuania was 3.2–3.6 cases per 100 000 children per year during the study period. Five-year probability of event-free survival increased from 50% ± 4% in 1992–1996 to 71% ± 4% in 2003–2008 (P |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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