NEW OPPORTUNITIES IN TREATMENT OF SEVERE SYSTEMIC TYPE OF JUVENILE ARTHRITIS
| Autor: | R.V. Denisova, E.I. Alexeeva, A.O. Lisitsin, S.I. Valieva, T.M. Bzarova |
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| Jazyk: | English<br />Russian |
| Rok vydání: | 2010 |
| Předmět: | |
| Zdroj: | Вопросы современной педиатрии, Vol 9, Iss 4, Pp 160-167 (2010) |
| Druh dokumentu: | article |
| ISSN: | 1682-5527 1682-5535 |
| Popis: | The article presents a case report of a severe clinical course of systemic type of juvenile arthritis, resistant to treatment with corticosteroids and classic immunosuppressive agents in girl 9 years old. Biological agent — tocilizumab showed beneficial effect: exudative lesions of joints, morning joint stiffness stopped and the range of motions restored in almost all affected joints in 8 weeks of treatment. A girl became more active, her emotional state improved. Laboratory signs of disease’s activity (ESR, concentration of C-reactive protein in plasma) were normalized in 4 weeks. The drug induced development of clinical and laboratory remission of a disease.Key words: children, juvenile arthritis, treatment, tocilizumab.(Voprosy sovremennoi pediatrii — Current Pediatrics. – 2010;9(4):160-167) |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
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