Generation of induced pluripotent stem cells from a patient with X-linked juvenile retinoschisis

Autor: Chi-Hsien Peng, Kang-Chieh Huang, Huai-En Lu, Shih-Han Syu, Aliaksandr A. Yarmishyn, Jyh-Feng Lu, Waradee Buddhakosai, Tai-Chi Lin, Chih-Chien Hsu, De-Kuang Hwang, Chia-Ning Shen, Shih-Jen Chen, Shih-Hwa Chiou
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Stem Cell Research, Vol 29, Iss , Pp 152-156 (2018)
Druh dokumentu: article
ISSN: 1873-5061
DOI: 10.1016/j.scr.2018.04.005
Popis: X-linked juvenile retinoschisis (XLRS) is a hereditary retinal dystrophy manifested as splitting of anatomical layers of retina. In this report, we generated a patient-specific induced pluripotent stem cell (iPSC) line, TVGH-iPSC-013-05, from the peripheral blood mononuclear cells of a male patient with XLRS by using the Sendai-virus delivery system. We believe that XLRS patient-specific iPSCs provide a powerful in vitro model for evaluating the pathological phenotypes of the disease.
Databáze: Directory of Open Access Journals