Residential radon and lung cancer: a cohort study in Galicia, Spain
| Autor: | Raquel Barbosa-Lorenzo, Alberto Ruano-Ravina, Sara Cerdeira-Caramés, Mónica Raíces-Aldrey, Juan M. Barros-Dios |
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| Jazyk: | English<br />Spanish; Castilian<br />Portuguese |
| Předmět: | |
| Zdroj: | Cadernos de Saúde Pública, Vol 33, Iss 6 |
| Druh dokumentu: | article |
| ISSN: | 1678-4464 0102-311x |
| DOI: | 10.1590/0102-311x00189415 |
| Popis: | Case-control studies show an association between residential radon and lung cancer. The aim of this paper is to investigate this association through a cohort study. We designed an ambispective cohort study using the Galician radon map, Spain, with controls drawn from a previous case-control study. Subjects were recruited between 2002 and 2009. The data were cross-checked to ascertain lung cancer incidence and then analysed using a Cox regression model. A total of 2,127 subjects participated; 24 lung cancer cases were identified; 76.6% of subjects were drawn from the radon map. The adjusted hazard ratio was 1.2 (95%CI: 0.5-2.8) for the category of subjects exposed to 50Bq/m3 or more. This risk rose when subjects from the case-control study were analyzed separately. In conclusion, we did not observe any statistically significant association between residential radon exposure and lung cancer; however, it appears that with a sample of greater median age (such as participants from the case-control study), the risk of lung cancer would have been higher. |
| Databáze: | Directory of Open Access Journals |
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