Non-controlled, open-label trial to assess clinical and immunological parameters in atopic dogs feeding monoprotein grain free diet versus a standard grain diet
| Autor: | María Teresa Verde, Sergio Villanueva-Saz, Laura Navarro, Araceli Loste, Diana Marteles, Antonio Fernández, Desirée Pereboom |
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| Jazyk: | angličtina |
| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Veterinary Quarterly, Vol 43, Iss 1, Pp 1-7 (2023) |
| Druh dokumentu: | article |
| ISSN: | 01652176 1875-5941 0165-2176 |
| DOI: | 10.1080/01652176.2023.2243309 |
| Popis: | AbstractCanine atopic dermatitis (cAD) is a common inflammatory skin disease that is treated with medicines or allergen-specific immunotherapy. An improvement diet can help treatment of cAD. The purpose of this study was compare two diets on clinical and immunological parameters in atopic dogs without food hypersensitivity. Diet A, a commercial based on rice, was offered to 22 atopic dogs during 30 days and Diet B (grain free, rich in salmon) was given to 8 atopic dogs. Clinical scores were assessed by CADESI-4 and PVAS at the beginning (T0) and at the end of the study (T30). CD4+ and CD8+ were measured in PBMCs, and serum cytokines (TNF-α, IL-10, IL-31 and IL-34) were determined. Both diets decreased CADESI-4 score and Diet A decreased PVAS score (p |
| Databáze: | Directory of Open Access Journals |
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