The Efficacy of Eradication of Helicobacter pylori Infection in Primary Prevention of NSAID-induced Gastropathy
| Autor: | S.M. Tkach, L.A. Onishchuk |
|---|---|
| Jazyk: | English<br />Ukrainian |
| Rok vydání: | 2015 |
| Předmět: | |
| Zdroj: | Gastroenterologìa, Vol 49, Iss 3.57, Pp 40-43 (2015) |
| Druh dokumentu: | article |
| ISSN: | 2308-2097 2518-7880 |
| DOI: | 10.22141/2308-2097.3.57.2015.81524 |
| Popis: | With the aim of clarifying the efficacy of eradication therapy for Helicobacter pylori (Hp) infection in primary prevention of NSAID-induced gastropathy, we have examined 39 Hp-positive patients, in whom we planned to administer non-steroidal anti-inflammatory drugs (NSAIDs) for various arthritis. In group I, non-steroidal anti-inflammatory drugs were prescribed after anti-helicobacter therapy, in group II eradication was not carried out, and the patients immediately received diclofenac. In both groups the incidence of peptic ulcers has been compared in 1 month after receiving diclofenac. In group I, peptic ulcers occurred in 2 patients (10.5 %), in group II — in 5 patients (26.3 %), ie in the group of eradication therapy they occurred significantly less frequently (χ2 = 0.5221). It is concluded that eradication of Hp-infection can be considered as an effective strategy for primary prevention of NSAID-induced gastropathy. |
| Databáze: | Directory of Open Access Journals |
| Externí odkaz: |
|