The extract of Cavendish banana (Musa acuminata) peel as antioxidant and anti-aging agents in model yeast Schizosaccharomyces pombe
| Autor: | Theresia Yolanda Avelina, Rika Indri Astuti, Wulan Tri WahyunI |
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| Jazyk: | English<br />Indonesian |
| Rok vydání: | 2024 |
| Předmět: | |
| Zdroj: | Menara Perkebunan, Vol 92, Iss 1, Pp 46-54 (2024) |
| Druh dokumentu: | article |
| ISSN: | 0125-9318 1858-3768 |
| DOI: | 10.22302/iribb.jur.mp.v92i1.565 |
| Popis: | Banana peel is one of the wastes that can be explored for various applications. Cavendish is among the most highly consumed bananas in the world, which implies a high amount of banana peel waste. Our study evaluated the potential of Cavendish banana peels as the source of antioxidant and anti-aging agents. Antioxidant was extracted using three different solvents, i.e., water, ethyl acetate, and methanol. Each extract was then assayed for antioxidant activity in vitro using a 1,1-diphenyl-2-picrylhydrazyl (DPPH) assay. The antioxidant and anti-aging activity of the extracts were further evaluated at the cellular level using the yeast Schizosaccharomyces pombe as a model. Our data indicated that the methanol extract of banana peel showed the highest antioxidant activity with an IC50 value of 253.8 µg mL-1 compared to ethyl acetate and water, yet it was considered weak. Interestingly, the methanol extract (600 ppm) showed antioxidant and anti-aging activities at cellular levels in yeast S. pombe. Therefore, this research reveals the potential for developing banana peel methanol extract as a component of pharmaceutical or cosmetic products with antioxidant and anti-aging properties. |
| Databáze: | Directory of Open Access Journals |
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