Autor: |
Matthew J. Burke, MD, Omar Ghaffar, MD, MSc, W. Richard Staines, PhD, Jonathan Downar, MD, PhD, Anthony Feinstein, MD, MPhil, PhD |
Jazyk: |
angličtina |
Rok vydání: |
2014 |
Předmět: |
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Zdroj: |
NeuroImage: Clinical, Vol 6, Iss C, Pp 333-339 (2014) |
Druh dokumentu: |
article |
ISSN: |
2213-1582 |
DOI: |
10.1016/j.nicl.2014.09.016 |
Popis: |
Background: Previous functional neuroimaging studies investigating the neuroanatomy of conversion disorder have yielded inconsistent results that may be attributed to small sample sizes and disparate methodologies. The objective of this study was to better define the functional neuroanatomical correlates of conversion disorder. Methods: Ten subjects meeting clinical criteria for unilateral sensory conversion disorder underwent fMRI during which a vibrotactile stimulus was applied to anesthetic and sensate areas. A block design was used with 4 s of stimulation followed by 26 s of rest, the pattern repeated 10 times. Event-related group averages of the BOLD response were compared between conditions. Results: All subjects were right-handed females, with a mean age of 41. Group analyses revealed 10 areas that had significantly greater activation (p |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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