Rh(III)-catalyzed [5+1] spirocyclization to produce novel benzimidazole-incorporated spirosuccinimides

Autor: Wei-Yi Pu, Xin-Yi Chen, Lin Dong
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Green Synthesis and Catalysis, Vol 4, Iss 4, Pp 338-341 (2023)
Druh dokumentu: article
ISSN: 2666-5549
DOI: 10.1016/j.gresc.2022.09.004
Popis: Transition-metal-catalyzed cross-coupling reactions as very efficient and atom-economical approaches have been widely used to build up complex heterocyclic compounds. However, modification of 2-oxyl benzimidazole skeleton using maleimide compounds via C–H activation has remained unprecedented. Herein, we developed a rhodium(III)-catalyzed [5 ​+ ​1] cascade spiroannulation to construct diversified novel benzimidazole-incorporated spirosuccinimide derivatives from 2-oxyl benzimidazoles and maleimides.
Databáze: Directory of Open Access Journals