| Autor: |
A.J. Baksi, J.E. Davies, N. Hadjiloizou, R. Baruah, B. Unsworth, R.A. Foale, K.H. Parker, D.P. Francis, J. Mayet, A.D. Hughes |
| Jazyk: |
angličtina |
| Rok vydání: |
2009 |
| Předmět: |
|
| Zdroj: |
Artery Research, Vol 3, Iss 4 (2009) |
| Druh dokumentu: |
article |
| ISSN: |
1876-4401 |
| DOI: |
10.1016/j.artres.2009.10.073 |
| Popis: |
Background: The Valsalva manoeuvre (VM) is a physiological manoeuvre capable of generating profound changes in venous return. Although its physiology has been extensively described, the predominant focus has been on dynamic effects on cardiac preload with subsequent impact on cardiac output. However, analysis of the dramatic changes seen in arterial pressure and flow during this manoeuvre offers valuable insight into arterial function. Methods: In 11 patients (9male, mean age 64 years), invasive measurement of pressure & Doppler flow velocity were made in the proximal aorta using sensor-tipped intra-arterial wires. Whilst recording, patients performed a controlled VM by blowing into a syringe. Calculation of pressure, aortic reservoir function and wave intensity were performed offline. Results: Peak systolic blood pressure fell on average by 24% during sustained VM (157±43mmHg to 122±48mmHg, p |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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