Hyperglycemia and Hypoglycemia Are Associated with In-Hospital Mortality among Patients with Coronavirus Disease 2019 Supported with Extracorporeal Membrane Oxygenation

Autor: Kuk Hui Son, Woong-Han Kim, Jae Gun Kwak, Chang-Hyu Choi, Seok In Lee, Ui Won Ko, Hyoung Soo Kim, Haeyoung Lee, Euy Suk Chung, Jae-Bum Kim, Woo Sung Jang, Jae Seung Jung, Jieon Kim, Young Kyung Yoon, Seunghwan Song, Minji Sung, Myung Hun Jang, Young Sam Kim, In-Seok Jeong, Do Wan Kim, Tae Yun Kim, Soon Jin Kim, Su Wan Kim, Joonhwa Hong, Hyungmi An, on behalf of The Korean Society for Thoracic and Cardiovascular Surgery COVID-19 ECMO Task Force Team
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Journal of Clinical Medicine, Vol 11, Iss 17, p 5106 (2022)
Druh dokumentu: article
ISSN: 2077-0383
DOI: 10.3390/jcm11175106
Popis: Metabolic abnormalities, such as preexisting diabetes or hyperglycemia or hypoglycemia during hospitalization aggravated the severity of COVID-19. We evaluated whether diabetes history, hyperglycemia before and during extracorporeal membrane oxygenation (ECMO) support, and hypoglycemia were risk factors for mortality in patients with COVID-19. This study included data on 195 patients with COVID-19, who were aged ≥19 years and were treated with ECMO. The proportion of patients with diabetes history among nonsurvivors was higher than that among survivors. Univariate Cox regression analysis showed that in-hospital mortality after ECMO support was associated with diabetes history, renal replacement therapy (RRT), and body mass index (BMI) < 18.5 kg/m2. Glucose at admission >200 mg/dL and glucose levels before ventilator >200 mg/dL were not associated with in-hospital mortality. However, glucose levels before ECMO >200 mg/dL and minimal glucose levels during hospitalization 200 mg/dL before ECMO and minimal glucose 200 mg/dL before ECMO and minimal glucose level
Databáze: Directory of Open Access Journals
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