Is there an association between colonisation of vancomycin resistant Enterococci, methicillin resistant Staphylococcus Aureus, or Clostridiodes Difficile and mortality in sepsis?

Autor: Matthew JG. Sigakis, Joseph Posluszny, Michael D. Maile, Elizabeth S. Jewell, Milo Engoren
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Infection Prevention in Practice, Vol 6, Iss 4, Pp 100413- (2024)
Druh dokumentu: article
ISSN: 2590-0889
DOI: 10.1016/j.infpip.2024.100413
Popis: Summary: Background: To determine if colonisation with drug resistant organisms is associated with worse outcomes in patients who subsequently develop sepsis. Methods: Retrospective study of patients with sepsis employing logistic regression and linear regression to determine the independent association of colonisation with adverse outcomes. Results: Mortality was higher in patients colonized with VRE [501 of 1937 (26%) v. 1052 of 5624 (19%) non-VRE colonised patients, difference 7% (95% confidence interval (5,9%), p
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