Meta-analysis of the clinical efficacy of low-concentrations atropine in controlling adolescent myopia

Autor: Jiang Zhidong, Cheng Lian, Zhang Yong, Liang Lei, Ruan Jinting, Huang Yanfei, Li Liangliang
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Guoji Yanke Zazhi, Vol 24, Iss 11, Pp 1784-1794 (2024)
Druh dokumentu: article
ISSN: 1672-5123
DOI: 10.3980/j.issn.1672-5123.2024.11.18
Popis: AIM: To systematically evaluate the efficacy and safety of low-concentrations atropine eye drops in controlling adolescent myopia.METHODS:A computer search was conducted on Wanfang Data, CNKI, VIP, PubMed, Cochrane Library, and Embase databases from January 2010 to March 2024 on clinical studies on low-concentration atropine eye drops for controlling adolescent myopia. Two researchers independently screened trials, extracted data, evaluated risk of bias and quality, and used Review Manager5.4 software to perform Meta-analysis.RESULTS:A total of 17 articles, involving 3 764 cases and 3 952 eyes, were included. The Meta-analysis showed that compared with the control group, low concentrations of atropine could effectively slow down the growth of axial length [MD=-0.15, 95% CI(-0.20, -0.10), P
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